Publications 2025

Chandosee Ganguly/University of Oklahoma, et al, Helical transition of the bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation , bioRxiv , (2026). 10.1101/2025.01.09.632262

Yongxiang Zhao/University of Utah School of Medicine, et al, Structural basis for human NKCC1 inhibition by loop diuretic drugs , The EMBO Journal 44, 1540-1562 (2025). 10.1038/s44318-025-00368-6

Yanyan Zhao/Stanford University, Michael F Schmid/SLAC National Accelerator Laboratory and Wah Chiu/Stanford University; SLAC National Accelerator Laboratory, Cost-benefit analysis of cryogenic electron tomography subtomogram averaging of chaperonin MmCpn at near atomic resolution , Structure 33, 372-380.e2 (2025). 10.1016/j.str.2024.11.008

Zhiyin Zhang/UC San Diego, et al, Design of light- and chemically responsive protein assemblies through host- guest interactions , Chem 11, (2025). 10.1016/j.chempr.2024.102407

Kankan Wang/Purdue University, et al, Molecular mechanisms of CAND2 in regulating SCF ubiquitin ligases , Nature Communications 16, 1998 (2025). 10.1038/s41467-025-57065-5

Adonis A Rubio/Stanford School of Medicine; Stanford University, et al, Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern , Science Translational Medicine 17, (2025). 10.1126/scitranslmed.adq5720

Zhang He/Stanford University School of Medicine, et al, Structure of mitochondrial pyruvate carrier and its inhibition mechanism , Nature 641, 250-257 (2025). 10.1038/s41586-025-08667-y

Rachael Kretsch/Stanford University, et al, Naturally ornate RNA-only complexes revealed by cryo-EM , Nature 643, 1135-1142 (2025). 10.1038/s41586-025-09073-0

Lauren Varanese/Stanford University School of Medicine, et al, MFSD6 is an entry receptor for enterovirus D68 , Nature 641, 1268-1275 (2025). 10.1038/s41586-025-08908-0

Ying-Hui Ko/The University of Alabama at Birmingham, et al, Ran modulates allosteric crosstalk between importin β surfaces , Nature Communications 16, 11425 (2025). 10.1038/s41467-025-66255-0